Title:
神経変性の治療における使用のための、グリシン/NMDAアンタゴニストとタキキニンNK-1受容体アンタゴニストとの組合わせ
Document Type and Number:
Japanese Patent JP2006525983
Kind Code:
A
Abstract:
The present invention relates to a pharmaceutical formulation comprising a compound which is active as an antagonist of the strychnine-insensitive glycine modulatory site of the N-methyl-D-asparate (NMDA) receptor in combination with a tachykinin NK-1 receptor antagonist, for use in the treatment of neurodegeneration arising, in particular, from stroke or cerebral ischemia.
Inventors:
Castro Pinero, Jose Lewis
Application Number:
JP2006506217A
Publication Date:
November 16, 2006
Filing Date:
May 04, 2004
Export Citation:
Assignee:
Merck Sharp End Dome Limited
International Classes:
A61K45/06; A61K31/498; A61K31/5355; A61K31/5377; A61P9/10; A61P25/00; A61P25/02; A61P25/04; A61P25/06; A61P25/08; A61P25/16; A61P25/18; A61P25/22; A61P25/24; A61P25/28; A61P25/30; A61P25/32; A61P27/02; A61P27/16; A61P43/00; C07D241/44; C07D401/14; C07D405/06
Attorney, Agent or Firm:
Yoshio Kawaguchi
Makoto Ono
Kenkyo Kanayama
Katsuma Osaki
Mitsuaki Tsubokura
Makoto Ono
Kenkyo Kanayama
Katsuma Osaki
Mitsuaki Tsubokura