Title:
Combination of phosphatidyl inositol 3-kinase (PI3K) inhibitor and mTOR inhibitor
Document Type and Number:
Japanese Patent JP6086902
Kind Code:
B2
Abstract:
The present invention relates to a pharmaceutical combination comprising a phosphatidylinositol-3-kinase (PI3K) inhibitor compound which is a 2-carboxamide cycloamino urea derivative or a pharmaceutically acceptable salt thereof and at least one mammalian target of rapamycin (mTOR) inhibitor or a pharmaceutically acceptable salt thereof; a pharmaceutical composition comprising such a combination; and the uses of such a combination in the treatment proliferative diseases, more specifically of mammalian target of rapamycin (mTOR) kinase dependent diseases.
Inventors:
Friche, christine
Chia-Echuberia, Carlos
Han Si Hong
Myra, Sauber-Michel
Chia-Echuberia, Carlos
Han Si Hong
Myra, Sauber-Michel
Application Number:
JP2014508463A
Publication Date:
March 01, 2017
Filing Date:
April 23, 2012
Export Citation:
Assignee:
Novartis Age
International Classes:
A61K31/4439; A61K31/436; A61P35/00; A61P43/00
Foreign References:
| WO2010029082A1 | ||||
| WO2010049481A1 |
Attorney, Agent or Firm:
Hiroshi Kobayashi
Eiji Katayama
Norio Omori
Tomohiro Maruyama
Yasuhito Suzuki
Eiji Katayama
Norio Omori
Tomohiro Maruyama
Yasuhito Suzuki
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