Title:
癌を治療するための併用療法
Document Type and Number:
Japanese Patent JP6963545
Kind Code:
B2
Abstract:
Provided are methods for treating cancer in a patient by administering at least one antibiotic selected from the group consisting of clofazimine, rifabutin and clarithromycin, in combination with an aryladamantane compound. In an embodiment, the aryladamantane compound is [3-(4-chlorophenyl)-adamantane-1-carboxylic acid (pyridin-4-ylmethyl)amide], or a pharmaceutically acceptable salt thereof.
Inventors:
Reza Fasi
Droll Ben-Asher
Daniel Abramson
Droll Ben-Asher
Daniel Abramson
Application Number:
JP2018517826A
Publication Date:
November 10, 2021
Filing Date:
October 06, 2016
Export Citation:
Assignee:
RedHill Biopharma Ltd.
International Classes:
A61K31/498; A61K31/4409; A61K31/495; A61K45/00; A61P35/00; A61P35/04; A61P43/00
Domestic Patent References:
| JP2008546714A | ||||
| JP2004536857A | ||||
| JP2007513062A | ||||
| JP2011511012A |
Foreign References:
| US20140314878 | ||||
| WO1995028939A1 |
Other References:
山田英史 ほか,14,15員環マクロライド抗菌剤の卵巣癌由来株に対する増殖能、浸潤能、血管新生能,日本癌治療学会誌,2000年,Vol. 35, No. 2,p. 557,P-956(1159)
山田英史 ほか,子宮体癌の血管新生、腫瘍増殖に対するClarithromycin(CAM)の効果,Japanese Journal of Cancer Research 日本癌学会総会記事 第59回総会(横浜),2000年,Vol. 91 Supplement,p. 347,2601
水島裕,今日の治療薬(2003年版),第25版,株式会社南江堂,2003年02月15日,第149頁
山田英史 ほか,子宮体癌の血管新生、腫瘍増殖に対するClarithromycin(CAM)の効果,Japanese Journal of Cancer Research 日本癌学会総会記事 第59回総会(横浜),2000年,Vol. 91 Supplement,p. 347,2601
水島裕,今日の治療薬(2003年版),第25版,株式会社南江堂,2003年02月15日,第149頁
Attorney, Agent or Firm:
Takuji Yamada
Kure Hidenori
Wataru Sato
Maho Ishibashi
Nagatoshi Shinagawa
Kure Hidenori
Wataru Sato
Maho Ishibashi
Nagatoshi Shinagawa
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