代謝性症候群ならびに関連の疾患および障害を治療するために、11β-ヒドロキシステロイドデヒドロゲナーゼ1型阻害剤および抗高血圧剤を使用する併用療法

Title:

Document Type and Number:

Japanese Patent JP2006522750

Kind Code:

A

Abstract:

Combination therapy comprising the administration of an 11ss-hydroxysteroid dehydrogenase type 1 inhibitor and an antihypertensive agent useful for treating, preventing and reducing the risk of developing insulin resistance, dyslipidemia, obesity, hypertension and other related diseases and disorders.

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Inventors:

Campen, Gita Camilla Tailgart
Andersen, Henrik Sneh

Application Number:

JP2006504357A

Publication Date:

October 05, 2006

Filing Date:

April 06, 2004

Export Citation:

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Assignee:

NOVO NORDISK AKTIE SELSXAB

International Classes:

A61K45/06; A61K31/138; A61K31/519; A61K31/55; A61P1/04; A61P1/14; A61P1/16; A61P3/00; A61P3/04; A61P3/06; A61P3/08; A61P3/10; A61P3/14; A61P5/38; A61P5/44; A61P5/46; A61P5/50; A61P7/06; A61P9/00; A61P9/04; A61P9/06; A61P9/10; A61P9/12; A61P11/00; A61P11/06; A61P13/12; A61P15/00; A61P15/08; A61P15/10; A61P17/02; A61P17/14; A61P19/02; A61P19/10; A61P21/00; A61P21/04; A61P25/00; A61P25/06; A61P25/08; A61P25/18; A61P25/22; A61P25/24; A61P25/28; A61P25/30; A61P27/02; A61P27/06; A61P29/00; A61P31/04; A61P31/10; A61P31/12; A61P33/00; A61P35/00; A61P35/02; A61P37/00; A61P37/02; A61P37/04; A61P41/00; A61P43/00; C07D401/14; C07D487/04

Domestic Patent References:

JP2006522749A	2006-10-05
JP2006522749A	2006-10-05

Other References:

JPN5006002739, ＲＥＥＤ　Ｐ　Ｉ, ＳＣＡＮＤＩＮＡＶＩＡＮ　ＪＯＵＲＮＡＬ　ＯＦ　ＧＡＳＴＲＯＥＮＴＥＲＯＬＯＧＹ．　ＳＵＰＰＬＥＭＥＮＴ, 1980, Ｖ１５　Ｎ６５, Ｐ５１−５６, ＳＣＡＮＤＩＮＡＶＩＡＮ　ＵＮＩＶＥＲＳＩＴＹ　ＰＲＥＳＳ
JPN7010001354, ＡＮＤＲＥＷＳ，Ｒ．Ｃ．　ｅｔ　ａｌ, "Ｅｆｆｅｃｔｓ　ｏｆ　ｔｈｅ　１１　ｂｅｔａ−ｈｙｄｒｏｘｙｓｔｅｒｏｉｄ　ｄｅｈｙｄｒｏｇｅｎａｓｅ　ｉｎｈｉｂｉｔｏｒ　ｃａｒｂｅｎｏｘｏｌｏｎｅ　ｏｎ　ｉｎｓｕｌｉｎ　ｓｅｎｓｉｔｉｖｉｔｙ　ｉ", Ｊ　Ｃｌｉｎ　Ｅｎｄｏｃｒｉｎｏｌ　Ｍｅｔａｂ, 2003, Ｖｏｌ．８８，　Ｎｏ．１, ｐ．２８５−９１
JPN6010024048, ＧＩＮＳＢＥＲＧ，Ｈ．Ｎ．, "Ｔｒｅａｔｍｅｎｔ　ｆｏｒ　ｐａｔｉｅｎｔｓ　ｗｉｔｈ　ｔｈｅ　ｍｅｔａｂｏｌｉｃ　ｓｙｎｄｒｏｍｅ", Ａｍ　Ｊ　Ｃａｒｄｉｏｌ, 200304, Ｖｏｌ．９１，　Ｎｏ．７Ａ, ｐ．２９Ｅ−３９Ｅ

Attorney, Agent or Firm:

Takehiko Suzue
Satoshi Kono
Makoto Nakamura
Kurata Masatoshi
Takashi Mine
Yoshihiro Fukuhara
Toshio Shirane
Sadao Muramatsu
Nobuhisa Nogawa
Ryo Hashimoto
Tetsuya Kazama

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