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Title:
COMBINATIONS OF ANTI-4-1BB ANTIBODIES AND ADCC-INDUCING ANTIBODIES FOR TREATMENT OF CANCER
Document Type and Number:
Japanese Patent JP2018115192
Kind Code:
A
Abstract:
PROBLEM TO BE SOLVED: To provide methods for treating cancer with combinations of antibodies.SOLUTION: A pharmaceutical composition for treatment of cancer contains a therapeutically effective amount of an anti-4-1BB agonist antibody or an antigen-binding portion thereof, in combination with a therapeutically effective amount of an anti-CD20 antibody or an antigen-binding portion thereof.SELECTED DRAWING: Figure 1

Inventors:
MARK WILLIAM ELLIOTT
FISHER TIMOTHY SCOTT
LESLIE LYNNE SHARP
Application Number:
JP2018056131A
Publication Date:
July 26, 2018
Filing Date:
March 23, 2018
Export Citation:
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Assignee:
PFIZER
International Classes:
A61K39/395; A61P35/00; A61P35/02; A61P43/00
Domestic Patent References:
JP6105470B22017-03-29
Foreign References:
WO2011071871A12011-06-16
Other References:
BLOOD, FEB 2011, 117(8):2423-32, JPN6016006673, ISSN: 0004110974
BLOOD, 2010, 116(21), ABSTRACT 422, JPN6016006674, ISSN: 0004110975
HAEMATOLOGICA, 2010, 95(SUPPL.2):305-6, ABSTRACT 0732, JPN6016006675, ISSN: 0004110976
Attorney, Agent or Firm:
Noh four
Junko Miyazawa
Maki Sato
Tatsuta Miyuki