Title:
特異性及び送達の改善のためのsiRNA分子、shRNA分子又はアンチセンス分子及び機能的実体を含む複合体
Document Type and Number:
Japanese Patent JP2008527993
Kind Code:
A
Abstract:
The present invention relates to modification of nucleic acids for specific delivery in vitro and in vivo. More specifically, the present invention relates to modification of RNA or DNA molecules in order to add functions in terms of delivery and specificity to RNA interference or antisense technology. A specific binding domain is incorporated into the nucleic acid to which a complementary nucleic acid, conjugated to a biologically active molecule, can hybridize.
Inventors:
Edvard smith
Matthias Svern
Auscar Simonson
Matthias Svern
Auscar Simonson
Application Number:
JP2007552091A
Publication Date:
July 31, 2008
Filing Date:
January 23, 2006
Export Citation:
Assignee:
Avaris Actie Borrag
International Classes:
C12N15/09; A61K31/7105; A61K31/711; A61K48/00; A61P31/12; A61P35/00; A61P43/00; C12N5/10; C12N15/11
Domestic Patent References:
| JP2002525066A | 2002-08-13 |
Foreign References:
| WO2004048545A2 | 2004-06-10 | |||
| WO2003091443A1 | 2003-11-06 |
Attorney, Agent or Firm:
Chika Takagi
Junji Yuda
Shoji Miwa
Noriyuki Takebayashi
Junji Yuda
Shoji Miwa
Noriyuki Takebayashi
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