To provide a polynucleotide useful for the diagnosis of esophageal cancer metastasis.
A composition for esophageal cancer diagnosis comprises two or more polynucleotides selected from the group consisting of a polynucleotide having recognizable change in the expression level of esophageal cancer cells with metastasis compared with esophageal cancer cells free from metastasis, its mutant, its fragment, a polynucleotide including a specific base sequence or its complementary sequence, its mutant, its fragment containing 15 or more of consecutive bases, a polynucleotide hybridizing with either one of the polynucleotides under a stringent condition, and its fragment. Further provided are a kit, a DNA chip, and a method for detecting or estimating the metastasis of esophageal cancer by using the composition, kit, or DNA chip.
TAEMOTO AKIRA
KOZONO SATOKO
AKIYAMA HIDEO
NOBUMASA HITOSHI
SHIMADA YUTAKA
TSUJIMOTO GOZO
UNIV KYOTO
Ishii Teiji
Satoshi Fujita
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