Title:
組成物及びその方法
Document Type and Number:
Japanese Patent JP7096813
Kind Code:
B2
Abstract:
Compounds of Formula I:or enantiomers thereof, metabolites thereof, derivatives thereof, deuterated derivatives thereof, prodrugs thereof, pharmaceutically acceptable salts thereof, N-oxides thereof, or a combination thereof, processes and intermediates for preparation thereof, compositions thereof, and uses thereof, are provided. Pharmaceutical compositions comprising a compound of formula I and a compound of Formula II:or enantiomers thereof, metabolites thereof, derivatives thereof, deuterated derivatives thereof, prodrugs thereof, pharmaceutically acceptable salts thereof, N-oxides thereof, or a combination thereof. Compositions and methods for improving the efficacy of DEX, or providing beneficial pharmacokinetic effects to DEX, comprising co-administering a compound of formula I or SARPO, and a compound of Formula II or DEX to a subject in need thereof, and dosage forms, drug delivery systems, methods of treatment thereof.
Inventors:
Vepacedu, Sulini Vasarao
Mobius, Hans Jay.
Besparov, Anton
Mobius, Hans Jay.
Besparov, Anton
Application Number:
JP2019510456A
Publication Date:
July 06, 2022
Filing Date:
August 25, 2017
Export Citation:
Assignee:
Exciva Game M Beher
Vepacedu, Sulini Vasarao
Vepacedu, Sulini Vasarao
International Classes:
A61K31/22; A61K9/08; A61K9/20; A61K9/48; A61K31/435; A61P25/00; A61P43/00
Domestic Patent References:
| JP2015522075A | ||||
| JP2016510762A | ||||
| JP2014129384A |
Other References:
Drug Metab Dispos,2014年,Vol.42,No.1,p.33-39
Attorney, Agent or Firm:
Yoshiyuki Inaba
Toshifumi Onuki
Akihiko Eguchi
Kazuhiko Naito
Toshifumi Onuki
Akihiko Eguchi
Kazuhiko Naito