Title:
ＣＹＰ４Ａ阻害化合物を有効成分として含む糖尿病及び脂肪肝の予防又は治療用組成物
Document Type and Number:
Japanese Patent JP6630401
Kind Code:
B2
Abstract:
The present invention relates to a pharmaceutical composition for the prevention or treatment of diabetes or fatty liver comprising a CYP4A (cytochrome P450A) inhibitor as an active ingredient. The compound of the present invention has activities of promoting glucose uptake into hepatocytes, inhibiting fat accumulation in liver cells, and inhibiting reactive oxygen production in mitochondria, and thus can be very usefully used for the development of a therapeutic agent for diabetes or fatty liver.
Inventors:
Kim, Gun Hwa
Park, Ju Hyun
Li, Minji
Park, Ju Hyun
Li, Minji
Application Number:
JP2018097829A
Publication Date:
January 15, 2020
Filing Date:
May 22, 2018
Export Citation:
Assignee:
KOREA BASIC SCIENCE INSTITUTE
International Classes:
A61K31/4545; A61K31/538; A61P1/16; A61P3/10
Domestic Patent References:
| JP2014521740A | ||||
| JP2011507910A |
Other References:
Gastroenterology,2014年,Vol.147,p.860-869
Attorney, Agent or Firm:
Heiwa International Patent Office