COMPOSITION FOR TREATING ARTICULAR CARTILAGE DAMAGE

Title:

COMPOSITION FOR TREATING ARTICULAR CARTILAGE DAMAGE

Document Type and Number:

Japanese Patent JP2012107026

Kind Code:

A

Abstract:

To provide a novel composition for treating articular cartilage damage constituted of a readily available cell and a biocompatible polymer, considering that treating methods of articular cartilage damage developed heretofore require a process for extracting bone marrow and have many problems from the viewpoints of operation processes and effects.

The composition for treating articular cartilage damage is constituted of a cell ingredient, which is isolated, proliferated or differentiated from umbilical cord blood, and a nutrient medium therefor. The cell ingredient is preferably at least one cell ingredient selected from among mesenchymal stem cell isolated from umbilical cord blood, a precursor cell which is derived from the mesenchymal stem cell and can be differentiated into a chondrocyte or an osteocyte, and a chondrocyte or an osteocyte differentiated from the mesenchymal stem cell. The biocompatible polymer is preferably at least one selected from among fibrin, gelatin, collagen, hyaluronic acid, polyphosphazine, polyacrylate, polyglactic acid, polyglycolic acid, pluronic acid, and alginic acid and a salt thereof.

Inventors:

HA CHUL-WON
YANG YOON-SUN
YANG SUNG-EUN

Application Number:

JP2012008349A

Publication Date:

June 07, 2012

Filing Date:

January 18, 2012

Export Citation:

Click for automatic bibliography generation Help

Assignee:

MEDIPOST CO LTD
HA CHUL WON

International Classes:

A61K35/14; A61K47/24; A61K35/44; A61K47/30; A61K47/32; A61K47/34; A61K47/36; A61K47/42; A61P19/02; C12N5/071; C12N5/0775

Domestic Patent References:

JP2001502905A	2001-03-06
JP2001502905A	2001-03-06

Foreign References:

WO1996028539A1	1996-09-19
WO2000012247A1	2000-03-09
WO1998051317A1	1998-11-19
WO2001034775A1	2001-05-17
WO1996028539A1	1996-09-19
WO2000012247A1	2000-03-09
WO1998051317A1	1998-11-19

Other References:

JPN6007004471; Ｊ．Ｂｉｏｍｅｄ．Ｍａｔｅｒ．Ｒｅｓ．　（２０００），　Ｖｏｌ．５０，　Ｎｏ．２，　ｐ．１０１-１０９
JPN6007004472; Ｊ．Ｂｉｏｍｅｄ．Ｍａｔｅｒ．Ｒｅｓ．　（２００１　Ａｐｒｉｌ），　Ｖｏｌ．５５，　Ｎｏ．１，　ｐ．１３-１９
JPN6007004473; Ａｒｃｈ．Ｏｔｏｌａｒｙｎｇｏｌ．Ｈｅａｄ．Ｎｅｃｋ．Ｓｕｒｇ．　（２０００），　Ｖｏｌ．１２６，　ｐ．１４４８-１４５２
JPN6007004474; Ｂｒ．Ｊ．Ｈａｅｍａｔｏｌ．　（２０００），　Ｖｏｌ．１０９，　Ｎｏ．１，　ｐ．２３５-２４２
JPN6007004471; Ｊ．Ｂｉｏｍｅｄ．Ｍａｔｅｒ．Ｒｅｓ．　（２０００），　Ｖｏｌ．５０，　Ｎｏ．２，　ｐ．１０１-１０９
JPN6007004472; Ｊ．Ｂｉｏｍｅｄ．Ｍａｔｅｒ．Ｒｅｓ．　（２００１　Ａｐｒｉｌ），　Ｖｏｌ．５５，　Ｎｏ．１，　ｐ．１３-１９
JPN6007004473; Ａｒｃｈ．Ｏｔｏｌａｒｙｎｇｏｌ．Ｈｅａｄ．Ｎｅｃｋ．Ｓｕｒｇ．　（２０００），　Ｖｏｌ．１２６，　ｐ．１４４８-１４５２
JPN6007004474; Ｂｒ．Ｊ．Ｈａｅｍａｔｏｌ．　（２０００），　Ｖｏｌ．１０９，　Ｎｏ．１，　ｐ．２３５-２４２

Attorney, Agent or Firm:

Kyousei Tamura
Samejima Mutsumi
Nagatoshi Shinagawa
Yasushi Morimoto

Previous Patent: DERIVATIVE OF 4-(2-AMINO-1-HYDROXYETHYL)PHENOL AS AGONIST OF BETA-2 ADRENERGIC RECEPTOR

Next Patent: ANTIMICROBIAL COMPOSITION CONTAINING SYNERGISTIC COMBINATION OF QUATERNARY AMMONIUM COMPOUND AND ESS...