Title:
瞳孔拡張を調節するための、フェントラミンを含む組成物及び方法
Document Type and Number:
Japanese Patent JP2013508383
Kind Code:
A
Abstract:
The disclosure provides a composition for controlling pupil dilation comprising about 0.001% to about 1.0% by weight of an alpha-adrenergic receptor antagonist selected from phentolamine, phentolamine mesylate, or a phentolamine salt; and at least one excipient selected from the group consisting of a buffer, tonicity agent, preservative, antioxidant, surfactant, solubilizer, cosolvent, and a combination thereof. A method of controlling pupil dilation in a subject in need thereof, comprising administering a therapeutically effective amount of the composition is also provided.
Inventors:
Lichtrous Anth Cone
Parachar Ajay Pee
Pujara Chetumpie
Parachar Ajay Pee
Pujara Chetumpie
Application Number:
JP2012535321A
Publication Date:
March 07, 2013
Filing Date:
October 20, 2010
Export Citation:
Assignee:
ALLERGAN,INCORPORATED
International Classes:
A61K31/417; A61K9/08; A61K9/107; A61K47/04; A61K47/18; A61K47/20; A61K47/22; A61K47/26; A61P27/02; A61P43/00
Attorney, Agent or Firm:
Koichi Tsujii
Sadao Kumakura
Atsushi Hakoda
Kenji Asai
Kazuo Yamazaki
Satsuki Ichikawa
Sadao Kumakura
Atsushi Hakoda
Kenji Asai
Kazuo Yamazaki
Satsuki Ichikawa