Title:
グルカゴン受容体抗体に関する組成物および方法
Document Type and Number:
Japanese Patent JP5513888
Kind Code:
B2
Abstract:
The present disclosure provides compositions and methods relating to antigen binding proteins, in particular, antibodies which specifically bind to the human glucagon receptor. The disclosure provides nucleic acids encoding such antigen binding proteins and antibodies and methods of making and using such antibodies including methods of treating and preventing type 2 diabetes and related disorders by administering such antibodies to a subject in need of such treatment.
Inventors:
Yang, high
Who, Shaw-Fen Sylvia
Boone, Thomas Sea
Lindberg, Richard A.
Who, Shaw-Fen Sylvia
Boone, Thomas Sea
Lindberg, Richard A.
Application Number:
JP2009529233A
Publication Date:
June 04, 2014
Filing Date:
September 19, 2007
Export Citation:
Assignee:
Amgen Incorporated
International Classes:
C07K16/28; A61K39/395; A61P3/06; A61P3/08; A61P3/10; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12N15/09; C12P21/08
Domestic Patent References:
| JP2001206899A |
Foreign References:
| WO2006005469A1 |
Other References:
BUGGY J,HORMONE AND METABOLIC RESEARCH,1996年,V28 N5,P215-219
WRIGHT L M,ACTA CRYSTALLOGRAPHICA. SECTION D, BIOLOGICAL CRYSTALLOGRAPHY,2000年 5月,V56 N.PT5,P573-580
WRIGHT L M,ACTA CRYSTALLOGRAPHICA. SECTION D, BIOLOGICAL CRYSTALLOGRAPHY,2000年 5月,V56 N.PT5,P573-580
Attorney, Agent or Firm:
Shinjiro Ono
Kazuo Shamoto
Yasushi Kobayashi
Akio Chiba
Hiroyuki Tomita
Hirose Shinobu
Kazuo Shamoto
Yasushi Kobayashi
Akio Chiba
Hiroyuki Tomita
Hirose Shinobu