Title:
癌及び感染症の免疫療法のための組成物及び方法
Document Type and Number:
Japanese Patent JP2008500005
Kind Code:
A
Abstract:
The present invention provides compositions and methods for the prevention and treatment of primary and metastatic neoplastic diseases and infectious diseases, for stimulating an immune response in a subject, and for use as an alternative to interleukin-12 (IL-12) treatment. In particular, the present invention provides Apicomplexa-related proteins (ARPs) that have immune stimulatory activity and thus have uses in the treatment and prevention of cancer and infectious diseases and in immune modulation. Compositions comprising an ARP are provided. Methods of use of an ARP for the prevention and/or treatment of cancer and/or infectious diseases, for use as an alternative to interleukin-12 (IL-12) treatment, and for eliciting an immune response in a subject, are also provided.
Inventors:
Isles Worth Charles
Hoshcheon
Jacket david
Judge John W
Rosenberg Burnett
Zlatkin Igor Buoy
Zlatkin Tatiana
Hoshcheon
Jacket david
Judge John W
Rosenberg Burnett
Zlatkin Igor Buoy
Zlatkin Tatiana
Application Number:
JP2006520402A
Publication Date:
January 10, 2008
Filing Date:
July 15, 2004
Export Citation:
Assignee:
Baros Research Institute
Michigan State University
Michigan State University
International Classes:
C12N15/09; A61K35/12; A61K38/00; A61K38/16; A61K39/012; A61K39/39; A61K48/00; A61P31/00; A61P31/04; A61P31/12; A61P31/16; A61P33/00; A61P33/02; A61P35/00; A61P37/04; C07K5/113; C07K7/06; C07K7/08; C07K14/455; C07K16/20; C12N1/19; C12N1/21; C12N5/10; C12P21/02; A61K39/00; C12P21/08
Domestic Patent References:
| JPH06504187A | 1994-05-19 |
Foreign References:
| WO2004020643A2 | 2004-03-11 |
Other References:
JPN6010024302, Ａｖｉａｎ Ｄｉｓ．，Ｖｏｌ．４４，Ｎｏ．２（２０００）ｐ．３７９−３８９
JPN6010024305, Ｍｏｌ．Ｂｉｏｃｈｅｍ．Ｐａｒａｓｉｔｏｌ．，Ｖｏｌ．６３，Ｎｏ．１（１９９４）ｐ．７９−８６
JPN6010024305, Ｍｏｌ．Ｂｉｏｃｈｅｍ．Ｐａｒａｓｉｔｏｌ．，Ｖｏｌ．６３，Ｎｏ．１（１９９４）ｐ．７９−８６
Attorney, Agent or Firm:
Masaki Hirota