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Title:
内在性免疫グロブリン遺伝子を阻害し、そして、トランスジェニック・ヒト・イディオタイプ抗体を製造するための組成物及び方法
Document Type and Number:
Japanese Patent JP6712254
Kind Code:
B2
Abstract:
The invention relates to transgenic animals lacking endogenous Ig and capable of producing transgenic antibodies, as well as methods of making the same. The invention further relates to methods for producing transgenic antibodies in such animals, and transgenic antibodies so produced.

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Inventors:
Burrow, Ronald
Application Number:
JP2017190442A
Publication Date:
June 17, 2020
Filing Date:
September 29, 2017
Export Citation:
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Assignee:
Open Monoclonal Technology, Incorporated
International Classes:
A01K67/027; A61K39/395; A61P31/00; A61P35/00; A61P37/06; A61P37/08; C12N15/90; C12P21/08
Domestic Patent References:
JP2007537130A
JP2004524841A
Foreign References:
WO2006093337A1
US20060153826
US20060117398
WO2005014650A1
Other References:
NGUYEN, V.K.,IMMUNOLOGY,2003年 5月,V109 N1,P93-101
Proc Natl Acad Sci U S A., (2006), Vol. 103, No. 41, p. 15130-15135
Attorney, Agent or Firm:
Atsushi Aoki
Takashi Ishida
Fukumoto product
Tetsuji Koga
Yoichi Watanabe
Ryotaro Takei
Masaru Nakajima



 
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