Title:
軟骨分解の全身阻害のための組成物および方法
Document Type and Number:
Japanese Patent JP2005519917
Kind Code:
A
Abstract:
Methods and compositions for inhibiting articular cartilage degradation. The compositions preferably include multiple chondroprotective agents, including at least one agent that promotes cartilage anabolic activity and at least one agent that inhibits cartilage catabolism. The compositions may also include one or more pain and inflammation inhibitory agents. The compositions may be administered systemically, such as to treat patients at risk of cartilage degradation at multiple joints, and suitably may be formulated in a carrier or delivery vehicle that is targeted to the joints. Alternatively the compositions may be injected or infused directly into the joint.
Inventors:
Demopros, Gregory A.
Palmer, Pamela earrings
Hearts, Jeffrey M.
Palmer, Pamela earrings
Hearts, Jeffrey M.
Application Number:
JP2003563495A
Publication Date:
July 07, 2005
Filing Date:
January 31, 2003
Export Citation:
Assignee:
Omeros Corporation
International Classes:
A61K9/14; A61K38/00; A61K38/22; A61K38/27; A61K39/395; A61K45/00; A61K45/06; A61K47/34; A61K47/36; A61K47/42; A61K47/48; A61P19/02; A61P19/04; A61P29/00; A61P41/00; (IPC1-7): A61K39/395; A61K9/14; A61K38/00; A61K38/22; A61K38/27; A61K45/00; A61K45/06; A61K47/34; A61K47/36; A61K47/42; A61P19/04
Domestic Patent References:
| JPH04502854A | 1992-05-28 |
Attorney, Agent or Firm:
Hidesaku Yamamoto
Takaaki Yasumura
Natsuki Morishita
Takaaki Yasumura
Natsuki Morishita