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Title:
COMPOSITIONS AND METHODS FOR PREVENTING OR TREATING MUSCLE CONDITIONS
Document Type and Number:
Japanese Patent JP2023139260
Kind Code:
A
Abstract:
To provide compositions for preventing or treating muscle conditions such as muscle damage, injury, or atrophy.SOLUTION: Compositions comprise a prostaglandin E2 (PGE2) compound and a myotoxin. The PGE2 compound is selected from the group consisting of PGE2, a PGE2 prodrug, a PGE2 receptor agonist, a compound that attenuates PGE2 catabolism, a compound that neutralizes PGE2 inhibition, a derivative thereof, an analog thereof, and a combination thereof. Methods of promoting muscle regeneration and methods of increasing muscle mass are also provided herein.SELECTED DRAWING: None

Inventors:
HELEN M BLAU
ANDREW TRI VAN HO
ADELAIDA R PALLA
HARVEY FISHMAN
CATHERINE CURTIN
CHRISTOPHER PAYNE
SCOTT DELP
VIVEK SHENOY
Application Number:
JP2023123301A
Publication Date:
October 03, 2023
Filing Date:
July 28, 2023
Export Citation:
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Assignee:
UNIV LELAND STANFORD JUNIOR
MYOFORTE THERAPEUTICS INC
International Classes:
A61K45/06; A61K31/245; A61K31/445; A61K31/46; A61K31/5575; A61K33/00; A61K33/06; A61K33/24; A61K33/32; A61K35/583; A61K35/64; A61K38/16; A61K38/17; A61K38/46; A61K39/395; A61P3/10; A61P13/02; A61P13/10; A61P21/00; A61P21/02; A61P23/00; A61P25/00; A61P27/02; A61P43/00
Attorney, Agent or Firm:
Hatsushi Shimizu
Hideki Kodera
Hirotaka Yamaguchi
Shun Jinbe
Ryuichi Inoue
Toshimitsu Sato
Koichi Niimi
Tomohiko Kobayashi
Masato Ozeki
Kazuya Kawamoto