ＣＮＳ障害を処置するための組成物および方法

Title:

ＣＮＳ障害を処置するための組成物および方法

Document Type and Number:

Japanese Patent JP7186259

Kind Code:

B2

Abstract:

Described herein are neuroactive steroids of the Formula (II):or a pharmaceutically acceptable salt thereof; wherein A, R¹, R^2a, R^2b, R^3a, R^3b, R^4a, R^4b, R⁵, R⁶and------are as defined herein. Such compounds are envisioned, in certain embodiments, to behave as GABA modulators. The present invention also provides pharmaceutical compositions comprising a compound of the present invention and methods of use and treatment, e.g., such for inducing sedation and/or anesthesia.

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Inventors:

Gabriel Martinez Boteja
Boyd El Harrison
Albert Jean Robi Show
Francesco Gee Salituro
Richard Thomas Veresis

Application Number:

JP2021090965A

Publication Date:

December 08, 2022

Filing Date:

May 31, 2021

Export Citation:

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Assignee:

Sage Therapeutics, Incorporated

International Classes:

A61K31/56; A61K31/568; A61K31/58; A61P23/00; A61P25/20

Domestic Patent References:

JP9510701A
JP2013173781A
JP2002506034A
JP6893173B2

Other References:

日本臨床(増刊),第71巻,増刊号5,2013年,pp.127-134

Attorney, Agent or Firm:

Shusaku Yamamoto
Morishita Natsuki
Takatoshi Iida
Daisuke Ishikawa
Kensaku Yamamoto

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