Title:
内寄生性生物防除剤である組成物
Document Type and Number:
Japanese Patent JP4033920
Kind Code:
B2
Abstract:
Endoparasitic activity of cyclic depsipeptides (I) comprising amino acid and hydroxycarboxylic acid units and having 6-30 ring atoms is increased by praziquantel (II) and epsiprantel (III). An endoparasitic agent contg. (I) together with (II) and (III) is also claimed. Known cpds. (I) are disclosed in EP382173 (depsipeptide PF 1022), WO9319053, J. Antibiotics 45 (1992) pp. 1207-1255 and pp 1273-1277, Helv. Chimn. Acta 46 (1963) pp 927-935 and pp 1715-1720, ibid, 47 (1964) pp. 166-173, Tetrahedron Letters 2 (1971) pp. 159-162, Biochem. Biophys. Res. Commun. 57 (1974) pp. 554-561 and Zh. Obshch. Khim. 41-(10) (10972) pp. 2320-2334. (II) is known from GB1441554 and (II) is known from EP134984 and EP185012.
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Inventors:
Norbert Menke
Achim Halder
Peter Yesuke
Achim Halder
Peter Yesuke
Application Number:
JP1633595A
Publication Date:
January 16, 2008
Filing Date:
January 09, 1995
Export Citation:
Assignee:
Bayer Aktiengesellschaft
International Classes:
A61K38/00; A61K38/08; C07D273/00; A61K31/41; A61K31/47; A61K31/495; A61K31/4985; A61K31/55; A61K38/15; A61P33/00; A61P33/10; C07K11/02
Domestic Patent References:
| JP3035796A | ||||
| JP57139012A |
Foreign References:
| WO1993025543A1 | ||||
| WO1992008468A1 |
Attorney, Agent or Firm:
Heikichi Odashima