Title:
ＴｒｋＡ阻害活性を有する化合物及びそれを活性成分として含有する疼痛を予防又は軽減するための医薬組成物
Document Type and Number:
Japanese Patent JP7132471
Kind Code:
B2
Abstract:
The present invention relates to a compound having TrkA inhibitory activity and a pharmaceutical composition for preventing or treating pain containing the same as an active ingredient. The compound provided in one aspect of the present invention has excellent TrkA inhibitory activity and exhibits excellent pain inhibitory effects in an animal model of pain after a surgery, and thus can be effectively used as an analgesic.
Inventors:
Jean, Bon Kyun
Application Number:
JP2021528310A
Publication Date:
September 07, 2022
Filing Date:
June 03, 2019
Export Citation:
Assignee:
JBKLAB CO.,LTD.
International Classes:
C07D471/04; A61K31/4545; A61K31/496; A61K31/519; A61P25/02; A61P25/04; A61P43/00; C07D487/04
Domestic Patent References:
| JP2004509891A | ||||
| JP2018507256A | ||||
| JP2006521336A | ||||
| JP2015522650A | ||||
| JP2013525363A |
Foreign References:
| KR1020170046847A | ||||
| KR101753654B1 | ||||
| US20080194557 | ||||
| WO2012135631A1 | ||||
| WO2018049200A1 | ||||
| US20050009876 |
Attorney, Agent or Firm:
Hiraki International Patent Office