Title:
COMPOUND HAVING HIGH AFFINITY TO CD22 MOLECULE AND ENHANCING PROLIFERATION OF B CELL
Document Type and Number:
Japanese Patent JP2011032180
Kind Code:
A
Abstract:
To provide a compound that has a high affinity to a CD22 molecule in a B cell and enhances immunoresponse to thereby exhibit activities including an activity of enhancing proliferation of the B cell and an activity of increasing resistance against infectious diseases such as virus-mediated diseases.
The compound is a sialic acid derivative represented by chemical formula (1) (wherein R1 and R2 are each an optionally substituted aromatic hydrocarbon group) or a prodrug thereof, or a pharmaceutically acceptable salt or hydrate thereof.
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Inventors:
TSUBATA TAKESHI
KISO MAKOTO
ISHIDA HIDEJI
ABDU-ALLAH HAJJAJ HASSAN MOHAMED
KISO MAKOTO
ISHIDA HIDEJI
ABDU-ALLAH HAJJAJ HASSAN MOHAMED
Application Number:
JP2009177776A
Publication Date:
February 17, 2011
Filing Date:
July 30, 2009
Export Citation:
Assignee:
JAPAN SCIENCE & TECH AGENCY
UNIV GIFU
UNIV GIFU
International Classes:
A61K31/7012; A61P37/04; C07H7/027
Attorney, Agent or Firm:
Masahiro Abe
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