COMPOUND HAVING MICROTUBULE POLYMERIZATION PROMOTING EFFECT OR MICROTUBULE POLYMERIZATION INHIBITING EFFECT

Title:

COMPOUND HAVING MICROTUBULE POLYMERIZATION PROMOTING EFFECT OR MICROTUBULE POLYMERIZATION INHIBITING EFFECT

Document Type and Number:

Japanese Patent JP2001247521

Kind Code:

A

Abstract:

To obtain a compound having microtubule polymerization promoting effect or microtubule polymerization inhibiting effect, having a simple chemical structure which can be supplied more stably than a compound having a taxane skeleton, further having high water solubility, and substitutable for taxol or taxotere.

A compound expressed by general formula [I] or [II], and having microtubule polymerization promoting effect or microtubule polymerization inhibiting effect (wherein, R1, R2, R3 and R4 are each hydroxyl, or a group convertible into hydroxyl; R5 and R6 are each a group selected from among a saturated hydrocarbon group, an unsaturated hydrocarbon group, a substituted saturated hydrocarbon group and a substituted unsaturated hydrocarbon group), or its salt.

Inventors:

NAMIKOSHI MICHIO
MEGURO SHIORI
KOBAYASHI HISAYOSHI
TAKAHASHI TAKENORI
OKANIWA KENICHIRO

Application Number:

JP2000057008A

Publication Date:

September 11, 2001

Filing Date:

March 02, 2000

Export Citation:

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Assignee:

KONISHIROKU PHOTO IND

International Classes:

C07H15/06; A61K31/23; A61K31/7028; A61K31/7032; A61P35/00; A61P43/00; C07C69/30; (IPC1-7): C07C69/30; A61K31/23; A61K31/7032; A61P35/00; A61P43/00; C07H15/06

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