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Title:
COMPOUND MONITORING BY ELECTROCHEMILUMINESCENCE TECHNIQUE
Document Type and Number:
Japanese Patent JP2007176939
Kind Code:
A
Abstract:

To provide a detectable compound comprising a first compound which is bonded to an electrochemiluminescent compound by a covalent bond and chemically transformable.

The compound is used for measuring the object to be analyzed in a sample and contains an electrochemiluminescent marker containing a metal coordination complex. In the compound, the marker is bonded to a catalyst substrate selected from β-lactams and β-nicotinamide adenine cofactors, but it is different from a catalyst product corresponding to the catalyst substrate in ability for generating the electrochemiluminescence in the electrochemiluminescent marker by reacting with the electrochemiluminescent marker. The compound is useful for a method and a kit for monitoring the state of the first compound and taking out information by the monitoring. The figure shows a proposal mechanism of ECL which describes reaction steps relating to use of TPA as a non-conjugated reductant.


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Inventors:
MARTIN MARK T
LIANG PAM
DONG LIWEN
Application Number:
JP2006335216A
Publication Date:
July 12, 2007
Filing Date:
December 13, 2006
Export Citation:
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Assignee:
IGEN INC
International Classes:
C07D499/46; C07D499/26; C07H23/00; C09K11/06; C12Q1/34; G01N21/78; G01N27/327; G01N27/42; C07F15/00
Attorney, Agent or Firm:
Hideto Asamura
Hajime Asamura
Yukihiro Ikeda
Naganuma Akio