COMPOUND FOR TREATMENT OF METABOLIC DISTURBANCE

Japanese Patent JP2009221232

A

To provide useful compounds for treatments of various metabolic disturbances (for example, insulin resistant syndromes, diabetes mellitus, hyperlipidemia, fatty liver diseases, cachexia, obesity, atherosclerosis and arterial sclerosis).

Biologically active drugs, namely the drugs are compounds shown by formula I or their pharmaceutically acceptable salts, wherein n represents 1 or 2, m represents 0 or 1, q represents 0 or 1, t represents 0 or 1, R9 represents a hydrogen, a halogen or 1-3C alkoxy, X represents -CH2- and Q represents -OR1, or X represents -CH2CR12CR13- or -CH2CH(NHAc)- and Q represents -OR1, or X represents -CH2CH2- and Q represents NR10R11.

SHARMA SHALINI
VON BORSTEL REID W
HODGE KIRVIN L
BAMAT MICHAEL K
WOLPE STEPHEN D

JP2009161270A

October 01, 2009

July 07, 2009

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WELLSTAT THERAPEUTICS CORP

A61K31/00; A61K31/16; A61K31/192; A61K31/165; A61K31/198; A61K31/216; A61K31/235; A61K31/27; A61K31/381; A61K31/41; A61K31/4196; A61K31/4402; A61K31/445; A61K31/535; A61K31/54; A61P1/16; A61P3/04; A61P3/06; A61P3/10; A61P7/00; A61P9/10; A61P9/12; A61P13/12; A61P17/02; A61P25/00; A61P27/02; A61P27/12; A61P35/00; C07C59/54; C07C59/68; C07C59/90; C07C69/738; C07C217/22; C07C233/47; C07C235/34; C07C235/78; C07C235/84; C07C237/32; C07C259/06; C07C323/47; C07C323/52; C07C323/59; C07C323/60; C07D213/30; C07D213/55; C07D249/10; C07D249/12; C07D257/04; C07D333/16; C07D333/22; C07D333/18

JPS5225734A	1977-02-25
JPS5515460A	1980-02-02

Hidesaku Yamamoto
Takaaki Yasumura
Natsuki Morishita

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