Title:
金属をキレート化するための化合物、放射性医薬、それらの製造方法、及び診断キット
Document Type and Number:
Japanese Patent JP2004514721
Kind Code:
A
Abstract:
The present invention provides a compound for chelating a metal or a metal complex, characterized in that it consists of a bis-dithiocarbamate structure (F) having the formula below: in which n and m are integers such that 5<=m+n<=10, X is chosen independently from S and NH, R1, R2, R3 and R4 are chosen independently from H and an organic function chosen from -COOR5, NR5R6 and -CH2OR5 in which R5 and R6, when it is present, are chosen independently from a hydrogen; an amino acid; a peptide; a protein; monoclonal antibody; a hormone; and a pharmaceutically acceptable vector. The present invention also provides a diagnostic kit comprising a chelating compound according to the present invention.
Inventors:
Moclair, Laurent
Bert mier, eric
Bert mier, eric
Application Number:
JP2002546545A
Publication Date:
May 20, 2004
Filing Date:
November 12, 2001
Export Citation:
Assignee:
Schering Actien Gezel Shaft
International Classes:
A61K31/27; A61K31/46; A61K31/555; A61K51/00; A61P25/16; C07B59/00; C07C333/14; C07D207/404; C07D207/50; C07D451/02; C07F1/08; C07F13/00; C07D207/40; (IPC1-7): C07C333/14; A61K31/27; A61K31/46; A61K31/555; A61K51/00; A61P25/16; C07D207/50; C07D451/02
Attorney, Agent or Firm:
Atsushi Aoki
Takashi Ishida
Tetsuji Koga
Yoichi Watanabe
Masaya Nishiyama
Takashi Ishida
Tetsuji Koga
Yoichi Watanabe
Masaya Nishiyama