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Title:
RAFキナーゼ阻害剤としての化合物および組成物
Document Type and Number:
Japanese Patent JP6636014
Kind Code:
B2
Abstract:
The present invention provides compounds of Formula (I) and (II) as described herein, and salts thereof, and therapeutic uses of these compounds for treatment of disorders associated with Raf kinase activity. The invention further provides pharmaceutical compositions comprising these compounds, and compositions comprising these compounds and a therapeutic co-agent.

Inventors:
Aversa, Robert John
Burger, Matthew Tea.
Dillon, Michael Patrick
Dinean Jr., Thomas A.
Lowe, Yang
Nishiguchi, Disel A
La Mercy, Savi Suri
Rico, Alice Sea.
Rauniar, Vivek
Martin
Sabra Manian, Sharada
Setch, Lina Quattrocio
Taft, Benjamin Earl.
Tanner, Howrowland
Wan, Liven
Application Number:
JP2017513627A
Publication Date:
January 29, 2020
Filing Date:
September 11, 2015
Export Citation:
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Assignee:
Novartis Age
International Classes:
C07D305/06; A61K31/337; A61K31/4375; A61K31/4427; A61K31/4433; A61K31/4439; A61K31/444; A61K31/4545; A61K31/497; A61K31/501; A61K31/5025; A61K31/506; A61K31/538; A61P35/00; A61P43/00; C07D405/10; C07D405/12; C07D405/14; C07D413/14; C07D471/04; C07D487/04
Domestic Patent References:
JP2016517417A
JP2007506696A
JP2008502666A
JP2011519940A
Foreign References:
CN102250065A
WO2009059272A1
Attorney, Agent or Firm:
Hiroshi Kobayashi
Eiji Katayama
Norio Omori
Kyoko Tamura
Yasuhito Suzuki