Title:
プロテインキナーゼ阻害剤としての化合物および組成物
Document Type and Number:
Japanese Patent JP2007500725
Kind Code:
A
Abstract:
The invention provides a novel class of compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with abnormal or deregulated kinase activity, particularly diseases or disorders that involve abnormal activation of the Abl, BCR-Abl, Bmx, c-Raf, Csk, Fes, FGFR, Flt3, Ikk, IR, JNK, Lck, Mkk, PKC, PKD, Rsk, SAPK, Syk, Trk, BTK, Src, EGFR, IGF, Mek, Ros and Tie2 kinases.
Inventors:
Sim Tebo
Lee Hyun Soo
Len Pinda
Din Kiang
Wan Sha
Tetsuro Uno
Jang Guobao
Liu Lee
Li Bin
Li Linton
Nathaniel S. Gray
You Shuri
Lee Hyun Soo
Len Pinda
Din Kiang
Wan Sha
Tetsuro Uno
Jang Guobao
Liu Lee
Li Bin
Li Linton
Nathaniel S. Gray
You Shuri
Application Number:
JP2006522114A
Publication Date:
January 18, 2007
Filing Date:
July 29, 2004
Export Citation:
Assignee:
IRM,LLC
International Classes:
C07D471/04; A61K31/5025; A61K31/519; A61K31/5377; A61P1/16; A61P7/02; A61P9/04; A61P9/10; A61P9/12; A61P11/06; A61P13/12; A61P17/00; A61P17/06; A61P19/02; A61P19/08; A61P19/10; A61P27/02; A61P29/00; A61P35/00; A61P35/02; A61P35/04; A61P37/00; A61P37/04; A61P37/06; A61P37/08; A61P39/02; A61P41/00; A61P43/00; C07D487/02; C07D487/04; A61K
Domestic Patent References:
| JP2003512378A | 2003-04-02 | |||
| JP2003509427A | 2003-03-11 | |||
| JP2002516327A | 2002-06-04 | |||
| JP2002528455A | 2002-09-03 |
Foreign References:
| WO2004041821A1 | 2004-05-21 |
Attorney, Agent or Firm:
Aoyama Aoi
Mitsutaka Iwasaki
Mitsutaka Iwasaki