Title:
タンパク質キナーゼ阻害剤としての化合物および組成物
Document Type and Number:
Japanese Patent JP5513558
Kind Code:
B2
Abstract:
The invention provides novel pyrimidine and pyridine derivatives of formula (I) and pharmaceutical compositions thereof, and methods for using such compounds. For example, the pyrimidine and pyridine derivatives of the invention may be used to treat, ameliorate or prevent a condition which responds to inhibition of anaplastic lymphoma kinase (ALK) activity, focal adhesion kinase (FAK), zeta-chain-associated protein kinase 70 ZAP-70), insulin-like growth factor (IGF- 1R), or a combination thereof.
Inventors:
Pierre-Eve Michelle
Pay way
Thomas H. Marsille
Wenshuo LU
Chen Bay
Tetsuro Uno
Jin Yunho
Jiang Tao
Pay way
Thomas H. Marsille
Wenshuo LU
Chen Bay
Tetsuro Uno
Jin Yunho
Jiang Tao
Application Number:
JP2012152703A
Publication Date:
June 04, 2014
Filing Date:
July 06, 2012
Export Citation:
Assignee:
IRM,LLC
International Classes:
C07D401/12; C07D471/04; C07D487/04; A61K31/44; A61K31/4545; A61K31/505; A61K31/506; A61K31/517; A61K31/519; A61K31/52; A61K31/5377; A61P35/00; A61P43/00; C07D213/74; C07D239/48; C07D401/14; C07D403/12; C07D403/14; C07D405/14; C07D413/12; C07D417/12; C07D451/02; C07D453/02; C07D473/16; C07D487/08
Domestic Patent References:
| JP2010512329A | ||||
| JP2006520354A | ||||
| JP2004516326A | ||||
| JP2003506375A | ||||
| JP11514336A | ||||
| JP2005523251A | ||||
| JP2004528314A | ||||
| JP2004524350A | ||||
| JP2005527529A |
Foreign References:
| WO2006021454A1 | ||||
| WO2005016894A1 | ||||
| WO2005016528A1 | ||||
| WO2005097135A1 | ||||
| US20050261295 |
Attorney, Agent or Firm:
Aoyama Aoi
Takuji Yamada
Michiko Matsutani
Mitsutaka Iwasaki
Satoshi Hashimoto
Takuji Yamada
Michiko Matsutani
Mitsutaka Iwasaki
Satoshi Hashimoto