治療薬の細胞内送達のための化合物及び組成物

Japanese Patent JP2024038014

A

【課題】新規な脂質及びそれを含む組成物を提供する。【解決手段】本開示のナノ粒子組成物は、新規な脂質、並びにリン脂質、構造脂質、及びＰＥＧ脂質などのさらなる脂質を含む。ＲＮＡなどの治療薬及び／または予防薬をさらに含むナノ粒子組成物が、例えば、ポリペプチド、タンパク質、または遺伝子発現を調節するための、哺乳動物細胞または器官への治療薬及び／または予防薬の送達に有用である。【選択図】図１

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WO/2005/037882	POLYMERS BASED ON N,N-DIALLYLAMINE DERIVATIVES, THEIR PRODUCTION AND USE
WO/1996/036371	POLYMER, ARTICLE AND METHOD FOR INHIBITING THE GROWTH OF OCULAR PATHOGENS IN EYE CARE PRODUCTS

Benenato, Kelly E.
Corne Vice, Mark
Hennessy, Edward

JP2023215826A

March 19, 2024

December 21, 2023

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ModernaTX,Inc.

C07C229/12; A61K9/127; A61K9/51; A61K31/7105; A61K47/10; A61K47/18; A61K47/22; A61K47/24; A61K47/28; C07C229/14; C07C229/16; C07C233/36; C07C235/10; C07C237/06; C07C239/20; C07C255/24; C07C271/22; C07C275/14; C07C279/24; C07C279/28; C07C279/36; C07C291/04; C07C307/06; C07C311/05; C07C311/47; C07C317/44; C07C335/08; C07D207/27; C07D207/404; C07D209/48; C07D233/61; C07D233/72; C07D239/47; C07D239/48; C07D239/54; C07D249/04; C07D263/22; C07D265/33; C07D271/06; C07D271/10; C07D277/42; C07D295/13; C07D295/135; C07D309/14; C07D473/18; C07D473/34; C07F7/10; C07F9/09; C12N15/88

Makoto Onda
Hironobu Onda
Atsushi Honda
Miki Nakamura

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