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Title:
眼障害及び皮膚疾患の処置のための化合物、組成物、及び方法
Document Type and Number:
Japanese Patent JP7038437
Kind Code:
B2
Abstract:
Disclosed is a compound of formula I or a pharmaceutically acceptable hydrate, solvate, crystal, co-crystal, enantiomer, stereoisomer, polymorph or prodrug thereof, which is useful for treatment of eye disorders, skin diseases and/or complications associated therewith. Also disclosed is a pharmaceutical composition comprising as an active ingredient at least one compound of formula I and a pharmaceutically acceptable excipient. Also disclosed is a method of treating an eye disorder, skin disease and/or a complication thereof in a subject in need thereof by administering at least one compound of formula I or a pharmaceutically acceptable hydrate, solvate, crystal, co-crystal, enantiomer, stereoisomer, polymorph or prodrug thereof.

Inventors:
Kandura Mahesh
Application Number:
JP2020526523A
Publication Date:
March 18, 2022
Filing Date:
November 10, 2018
Export Citation:
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Assignee:
CELLIX BIO PRIVATE LIMITED
International Classes:
C07D339/04; A61K31/216; A61K31/382; A61K31/385; A61K31/416; A61K31/4164; A61K31/439; A61K31/4409; A61K31/498; A61K31/5377; A61K31/5383; A61K31/542; A61K31/5575; A61K47/55; A61P17/00; A61P17/06; A61P27/02; A61P27/06; A61P27/12; C07D213/40; C07D231/56; C07D233/10; C07D403/12; C07D417/04; C07D453/02; C07D495/04; C07D498/04; C07D513/04
Domestic Patent References:
JP2016508140A
JP2004537522A
Foreign References:
WO2015103577A1
WO2010125416A1
CN104387364A
US20090156606
US20140221467
Other References:
MENDES DE FREITAS, Rivelilson,Lipoic Acid Increases Hippocampal Choline Acetyltransferase and Acetylcholinesterase Activities and,Neurochem Res,2010年,Vol.35,pp.162-170,DOI:10.1007/s11064-009-0041-6
FREITAS, R. M.,The evaluation of effects of lipoic acid on the lipid peroxidation, nitrite formation and antioxidan,Neuroscience Letters,2009年,Vol.455,pp.140-144,DOI:10.1016/j.neulet.2009.03.065
Attorney, Agent or Firm:
Patent Business Corporation Saegusa International Patent Office