Title:
化合物、組成物および方法
Document Type and Number:
Japanese Patent JP4613157
Kind Code:
B2
Abstract:
Certain substituted urea derivatives selectively modulate the cardiac sarcomere, for example by potentiating cardiac myosin, and are useful in the treatment of systolic heart failure including congestive heart failure.
Inventors:
Morgan, bradley, paul
Elias, Kathleen, A.
Craneac, Erica, Anne
Lou, Pooh-Ping
Marrick, Fady
Mousie, Alex
Kian, Champin
Smith, Whitney, Walter
Tochimoto, Todd
Thomas, adam, lewis
Morgans, David, Jay., Jr.
Elias, Kathleen, A.
Craneac, Erica, Anne
Lou, Pooh-Ping
Marrick, Fady
Mousie, Alex
Kian, Champin
Smith, Whitney, Walter
Tochimoto, Todd
Thomas, adam, lewis
Morgans, David, Jay., Jr.
Application Number:
JP2006500973A
Publication Date:
January 12, 2011
Filing Date:
January 14, 2004
Export Citation:
Assignee:
Cytokinetics Incorporated
International Classes:
C07D401/12; A61K31/17; A61K31/34; A61K31/35; A61K31/424; A61K31/44; A61K31/4439; A61K31/4545; A61K31/5377; C07C273/02; C07C275/28; C07C275/30; C07C275/34; C07C275/36; C07C275/40; C07D207/12; C07D211/42; C07D213/02; C07D213/65; C07D213/70; C07D213/75; C07D217/04; C07D405/12; C07D413/02; C07D413/12; C07D417/12; C07D498/04; C07D513/04; A61K
Domestic Patent References:
| JP2001526276A |
Foreign References:
| WO1998050346A1 | ||||
| US5162360 | ||||
| US4405644 |
Attorney, Agent or Firm:
Yusuke Hiraki
Ishii Teiji
Satoshi Fujita
Ishii Teiji
Satoshi Fujita