Title:
陽電子放出断層撮影用の化合物
Document Type and Number:
Japanese Patent JP7299285
Kind Code:
B2
Abstract:
Described herein are compounds, compositions, and methods for diagnosing and/or monitoring pathogenic disease using positron emission tomography. Also described are conjugates of the formula B-L-P, wherein B is a radical of a targeting agent selected from vitamin receptor binding ligands (such as folate), PSMA binding ligands, or PSMA inhibitors; L is a divalent linker comprising aspartic acid, lysine, or arginine, and P is a radical of an imaging agent or radiotherapy agent, such as a radionuclide or radionuclide containing group, or a radical of a compound capable of binding a radionuclide, such as a metal chelating group.
Inventors:
Ion Choar Brahoff
Christopher Pee Liemon
Philip S. Low
Garth El Param
Chinsho Chen
Christopher Pee Liemon
Philip S. Low
Garth El Param
Chinsho Chen
Application Number:
JP2021175168A
Publication Date:
June 27, 2023
Filing Date:
October 27, 2021
Export Citation:
Assignee:
ENDOCYTE, INC.
PURDUE RESEARCH FOUNDATION
PURDUE RESEARCH FOUNDATION
International Classes:
C07D255/02; A61K47/54; A61K47/64; A61K47/65; A61K47/69; A61K51/00; A61K51/04; A61K51/08; G01T1/161
Foreign References:
| WO2010108125A1 |
Other References:
Journal of Labelled Compounds and Radiopharmaceuticals,2012年07月09日,Vol.55,pp.320-325
EJNMMI Research,2013年05月08日,Vol.3,Article Number:36, pp.1-11
EJNMMI Research,2013年05月08日,Vol.3,Article Number:36, pp.1-11
Attorney, Agent or Firm:
Koji Murai
Kaori Horikawa
Kaori Horikawa