Title:
PPAR受容体及びEGF受容体に特異的な化合物及びそれらの塩並びに医療分野におけるそれらの使用
Document Type and Number:
Japanese Patent JP5193862
Kind Code:
B2
Abstract:
The present invention relates to compounds of formula (I), where R1 and R2, which may be identical or different, are selected from the group comprising H, CnH2n-1, a linear or branched alkyl group having 1 to 6 carbons, or together form an aromatic or aliphatic ring with 5 or 6 atoms; R3 is -CO-CH3, -NHOH, -OH, or -OR6 where R6 is a linear or branched alkyl group having 1 to 6 carbon atoms; R4 is H, linear or branched alkyl group having from 1 to 6 atoms, phenyl, benzyl, -CF3 or CF2CF3, vinyl or allyl; R5, R7, R8 are hydrogen atoms; or R3 and R4, R4 and R5, or R7 and R8 together form a ring, fused to the benzene, aromatic or aliphatic ring with 5 or 6 atoms comprising from 1 to 2 heteroatoms selected independently from the group comprising N, O, and use thereof in the medical field.
Inventors:
Nakkari, Giancarlo
Baroni, Sergio
Baroni, Sergio
Application Number:
JP2008522168A
Publication Date:
May 08, 2013
Filing Date:
July 24, 2006
Export Citation:
Assignee:
Giuliani International Limited
International Classes:
C07C229/64; A61K31/166; A61K31/196; A61K31/343; A61K31/357; A61K31/47; A61P1/04; A61P35/00; C07C259/10; C07D215/48; C07D307/79; C07D319/08
Domestic Patent References:
| JP2000503643A | ||||
| JP11506114A | ||||
| JP7509234A | ||||
| JP59065040A | ||||
| JP53059669A |
Foreign References:
| WO1999015520A1 | ||||
| WO2005011685A1 | ||||
| US3444232 |
Other References:
Journal of Experimental Medicine,2005年 4月11日,201(8),p.1205-1215
Attorney, Agent or Firm:
Hideto Asamura
Hajime Asamura
Yuko Nagase
Yukihiro Ikeda
Hajime Asamura
Yuko Nagase
Yukihiro Ikeda