Title:
非自己免疫性2型糖尿病および/またはX症候群の処置のための化合物
Document Type and Number:
Japanese Patent JP2008543903
Kind Code:
A
Abstract:
The present invention relates to compounds of the formula (I); wherein R1 is H, CH3 or OCH3; R3=H, OH, CH3, OCH3, O-glucose or benzoyloxy; R4=H; R5=H or OH; R6=H or OCH3; R7=H, CH3, OCH3, cinnamoyloxy or (3,4,5-trimethoxy)-benzoyloxy; R8=H, OH, CH3 or OCH3; or R7 and R8 form together a group 0-CH2-O; R9=H or OCH3; R10=H or N-acetyl, N-methyl-2-aminoethyl; to their use as medicament for the treatment of non-autoimmune type 2 diabetes mellitus and/or syndrome X, to dietary and pharmaceutical compositions containing them and to a method for the treatment of non-autoimmune type 2 diabetes mellitus and/or syndrome X in animals including humans, said method comprising the step of administering an effective dose of a compound of the formula (I) to animals including humans which are in need thereof.
Inventors:
Duo radio, daniel
Desai Dieu, Antoin
Raederstov, Daniel
Schuler, godet
One-Schmidt, Inn
Weri, Christoph
Werz, Karin
Wolfram, Swen
Desai Dieu, Antoin
Raederstov, Daniel
Schuler, godet
One-Schmidt, Inn
Weri, Christoph
Werz, Karin
Wolfram, Swen
Application Number:
JP2008517424A
Publication Date:
December 04, 2008
Filing Date:
June 23, 2006
Export Citation:
Assignee:
DSM IP ASSETS B.V.
International Classes:
C07C69/618; A61K31/121; A61K31/216; A61K31/235; A61K31/36; A61P3/04; A61P3/06; A61P3/10; A61P9/10; A61P9/12; A61P43/00; C07C69/78; C07D317/64
Domestic Patent References:
| JP2003252784A | 2003-09-10 | |||
| JPH02264718A | 1990-10-29 | |||
| JPH04297418A | 1992-10-21 | |||
| JPS63104912A | 1988-05-10 | |||
| JPH1192466A | 1999-04-06 | |||
| JPH0585945A | 1993-04-06 | |||
| JP2001058969A | 2001-03-06 | |||
| JPH0624975A | 1994-02-01 | |||
| JPH11349521A | 1999-12-21 |
Foreign References:
| US20040209952A1 | 2004-10-21 | |||
| EP0370461A2 | 1990-05-30 |
Attorney, Agent or Firm:
Yuichi Yamada
Masakazu Noda
Yoshinori Shimizu
Ikeda adult
Masakazu Noda
Yoshinori Shimizu
Ikeda adult