Title:
縮合複素環誘導体及びその医薬用途
Document Type and Number:
Japanese Patent JP5587784
Kind Code:
B2
Abstract:
The present invention provides compounds useful as agents for the prevention or treatment of a disease associated with abnormal plasma uric acid level and the like. The present invention relates to fused heterocyclic derivatives represented by the following formula (I) having xanthine oxidase inhibitory activities and useful as agents for the prevention or treatment of a disease associated with abnormality of plasma uric acid level, prodrugs thereof, salts thereof or the like. In the formula (I), T represents trifluoromethyl, nitro or cyano; ring Q represents heteroaryl; X 1 and X 2 independently represent CH or N; ring U represents aryl or heteroaryl; m represents integral number from 0 to 2; n represents integral number from 0 to 3; R 1 represents a hydroxy group, amino or C 1-6 alkyl; R 2 represents C 1-6 alkyl, C 1-6 alkoxy C 1-6 alkyl or the like.
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Inventors:
Kazuo Shimizu
Iizuka Masato
Hideki Fujikura
Takikawa 靖
平栃 Masahiro
Iizuka Masato
Hideki Fujikura
Takikawa 靖
平栃 Masahiro
Application Number:
JP2010533902A
Publication Date:
September 10, 2014
Filing Date:
October 14, 2009
Export Citation:
Assignee:
KISSEI PHARMACEUTICAL CO., LTD.
International Classes:
C07D401/04; A61K31/427; A61K31/443; A61K31/4439; A61K31/4709; A61K31/4725; A61P13/04; A61P13/12; A61P19/02; A61P19/06; A61P43/00; C07D405/04; C07D417/04
Foreign References:
| WO2006100095A1 | 2006-09-28 | |||
| GB1398800A | 1975-06-25 | |||
| WO2006100095A1 | 2006-09-28 | |||
| GB1398800A | 1975-06-25 |
Attorney, Agent or Firm:
Willow Nobuko
Willow Nobuko
Willow Nobuko
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