Title:
バニロイド受容体サブタイプ1(VR1)受容体を阻害する縮合アザ二環式化合物
Document Type and Number:
Japanese Patent JP4614662
Kind Code:
B2
Abstract:
Compounds of formula (I), are novel VR1 antagonists that are useful in treating pain, inflammatory thermal hyperalgesia, urinary incontinence and bladder overactivity.
Inventors:
Lee, Chi-Han
Bybert eror kay
Dade Menico, Stanley Giunia
Drizin, Irene
Gomutsuyan, Arthur Earl
Corniche, Jiyoung Earl
Planner, Littleyard
Robert Smith
Turner, Shion Sea
White, Tammy Kay
Guo Chi Yu
Bybert eror kay
Dade Menico, Stanley Giunia
Drizin, Irene
Gomutsuyan, Arthur Earl
Corniche, Jiyoung Earl
Planner, Littleyard
Robert Smith
Turner, Shion Sea
White, Tammy Kay
Guo Chi Yu
Application Number:
JP2003569203A
Publication Date:
January 19, 2011
Filing Date:
February 11, 2003
Export Citation:
Assignee:
ABBOTT LABORATORIES
International Classes:
C07D231/56; A61K31/404; A61K31/416; A61K31/47; A61K31/472; A61K31/496; A61K31/5377; A61K31/541; C07D209/08; C07D217/02; C07D217/22; C07D217/24; C07D217/26; C07D237/28; C07D401/12; C07D405/12; C07D409/12; C07D413/12; C07D417/12; C07D521/00; A61K31/4045; A61K31/4725; A61K31/502; A61K31/55; A61P13/10; A61P25/02; A61P29/00; A61P43/00; C07D209/28
Domestic Patent References:
| JP62116559A | ||||
| JP2001122895A | ||||
| JP3120243A | ||||
| JP10087629A | ||||
| JP64031766A | ||||
| JP5504968A | ||||
| JP62500168A | ||||
| JP2003192587A | ||||
| JP2005517672A | ||||
| JP2004339061A | ||||
| JP2005518371A | ||||
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| JP2005516951A | ||||
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| JP9511215A | ||||
| JP2007501246A |
Foreign References:
| WO2001066520A1 | ||||
| US3043694 | ||||
| EP0013411A1 | ||||
| FR1344579B1 | ||||
| WO2002008221A1 | ||||
| WO2002100819A1 | ||||
| WO2001098269A1 | ||||
| WO1993009102A1 |
Other References:
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GALL, R et al,HELV CHIM ACTA,1955年,vol. 38, no. 171,,pages 1421-1423
HELV CHIM ACTA,1954年,vol. 37,,pages 90-94
J AMER CHEM SOC,1935年,vol. 57, ,pages 1840-1844
CANADIAN JOURNAL OF CHEMISTRY,1971年,vol. 49, no. 24,pages 4054-4061
J MED CHEM,1974年,vol. 17, no. 11,pages 1145-1150
J AM CHEM SOC,1942年,vol. 64,pages 783-784
CHEMICAL AND PHARMACEUTICAL BULLETIN,1972年,vol. 20, no. 10,pages 2163-2171
J HETEROCYCLIC CHEMISTRY,1982年,vol. 19,,pages 1195-1199
INDIAN JOURNAL OF CHEMISTRY,1992年,vol. 31b,pages 177-182
JOURNAL OF MEDICINAL CHEMISTRY,1993年,vol. 36,pages 1104-1107
Tetrahedron Letters,1981年,vol.22, No.44,4397-4400
Chemical Abstracts,1985年,vol.102,Abstract No.113361
Chemical Abstracts,1983年,vol.99,Abstract No.533289
Attorney, Agent or Firm:
Yoshio Kawaguchi
Akio Ichiiri
Makoto Ono
Katsuma Osaki
Mitsuaki Tsubokura
Akio Ichiiri
Makoto Ono
Katsuma Osaki
Mitsuaki Tsubokura