Title:
縮合テトラヒドロキノリン誘導体及びその医薬用途
Document Type and Number:
Japanese Patent JP5328371
Kind Code:
B2
Abstract:
The problem of the present invention is to provide a compound having a GR selective binding activity, which shows less action on other nuclear receptors such as progesterone receptor (PR), mineralocorticoid receptor (MR) and the like. The present invention provides a condensed tetrahydroquinoline compound represented by the following formula (I)
wherein each symbol is as defined in the present specification, or a pharmaceutically acceptable salt thereof or a hydrate thereof.
Inventors:
Masahiro Eda
Tomoko Kuroda
Keiichi Aritomo
Yoshiyuki Aoki
Satoshi Kaneko
Tomoko Kuroda
Keiichi Aritomo
Yoshiyuki Aoki
Satoshi Kaneko
Application Number:
JP2008554034A
Publication Date:
October 30, 2013
Filing Date:
January 15, 2008
Export Citation:
Assignee:
Mitsubishi Tanabe Pharma Corporation
International Classes:
C07D221/16; A61K31/473; A61K31/4741; A61K31/4985; A61K31/502; A61P25/00; A61P25/18; A61P25/22; A61P25/24; C07D401/04; C07D409/04; C07D413/04; C07D471/04; C07D487/04; C07D491/056; C07D495/04; C07D519/00
Domestic Patent References:
| JPH10510840A | 1998-10-20 | |||
| JPH10510840A | 1998-10-20 |
Foreign References:
| WO2006019716A1 | 2006-02-23 | |||
| WO2005087769A1 | 2005-09-22 | |||
| WO2006019716A1 | 2006-02-23 | |||
| WO2005087769A1 | 2005-09-22 |
Attorney, Agent or Firm:
Takashima Ichi
Kyoko Doi
Mitsunori Kamata
Yaeko Tamura
Kenji Yamamoto
Murata Miyuki
Kyoko Doi
Mitsunori Kamata
Yaeko Tamura
Kenji Yamamoto
Murata Miyuki