Title:
CONTRACEPTIVE METHOD THAT DOES NOT INFLUENCE MENSTRUAL CYCLE
Document Type and Number:
Japanese Patent JPH05112467
Kind Code:
A
Abstract:
PURPOSE: To practice reliable contraception by administering an aromatase inhibitor in such a dose that it gives no influence on menstrual cycle of a female primate. CONSTITUTION: The present invention provides a method for contraception in a female primate excluding a human in reproducible ages. To the female primate, an aromatase inhibitor such as 5-(p-cyanophenyl)-5,6,7,8- tetrahydrimidazo[1,5-a]pyridine is administered in such a dose that it does not substantially affect menstrual cycle of the female primate to practice contrception. Further, the aromatase inhibitor preferably exhibit an IC50 -value of <=10<-5> in terms of in vitro inhibition of an aromatase activity.
Inventors:
AJIYAI BAATONAGAA
Application Number:
JP9968792A
Publication Date:
May 07, 1993
Filing Date:
April 20, 1992
Export Citation:
Assignee:
CIBA GEIGY AG
International Classes:
A61K31/00; A61K31/41; A61K31/415; A61K31/425; A61K31/435; A61K31/44; A61K45/00; A61K31/34; A61P43/00; C07D471/04; (IPC1-7): A61K31/34; A61K31/41; A61K31/415; A61K31/425; A61K31/435; A61K45/00; C07D471/04
Attorney, Agent or Firm:
Aoki Akira (3 outside)