Title:
α-ヒドロキシ酸由来のO-カルボキシ無水物の制御された重合方法
Document Type and Number:
Japanese Patent JP5167815
Kind Code:
B2
Abstract:
The invention concerns a method for preparing poly(-hydroxy acids), the polymerization reaction being performed in controlled manner in the presence of a catalytic system including a base, said base being a 5- or 6-membered aromatic heterocycle comprising at least one endocyclic nitrogen atom, provided that when the base is used alone in the catalytic system, it does not represent pyridine, 2-methylpyridine, 2,6-dimethylpyridine or 2-methoxypyridine. The invention also concerns poly(-hydroxy acids) of formula (IV). Finally, the invention concerns the use of a poly(-hydroxy acid), obtainable by the inventive method, for vectoring active principles or for making biomaterials.
Inventors:
Bliss, Didier
Tilley du Bure, Olivier
Marshall, Emmanuel
Martin-Baka, Bianca
Tilley du Bure, Olivier
Marshall, Emmanuel
Martin-Baka, Bianca
Application Number:
JP2007535179A
Publication Date:
March 21, 2013
Filing Date:
October 07, 2005
Export Citation:
Assignee:
Isochem
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE(CNRS)
Universite Paul Sabatiel Toulouse Trois
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE(CNRS)
Universite Paul Sabatiel Toulouse Trois
International Classes:
C08G63/08; A61K47/34; A61L17/00; A61L27/00; C07C67/465; C07C69/675; C08G63/81; C08G63/87
Domestic Patent References:
| JP40002333B1 | ||||
| JP7502772A | ||||
| JP8301994A | ||||
| JP5271051A | ||||
| JP2002284870A | ||||
| JP9040761A | ||||
| JP2004131692A |
Foreign References:
| US2371281 |
Other References:
Tertiary Base Initiated Polymerisation of 5-Phenyl-1,3-dioxolan-2,4-dione,Makromol.Chem.,1981年,182
Hans R. Kricheldorf,Synthesis and Polymerization of L-Lactic Acid O-Carboxyanhydride (5-Methyl-Dioxolan-2,4-dione),Polymer Bulletin,1983年,9,276-283
Hans R. Kricheldorf,Synthesis and Polymerization of L-Lactic Acid O-Carboxyanhydride (5-Methyl-Dioxolan-2,4-dione),Polymer Bulletin,1983年,9,276-283
Attorney, Agent or Firm:
Shoichi Hirose