Title:
フェノール性オピオイドの制御放出
Document Type and Number:
Japanese Patent JP5371746
Kind Code:
B2
Abstract:
The present invention relates to a method of providing a patient with controlled release of a phenolic opioid using a prodrug capable, upon enzymatic activation, of releasing the phenolic opioid through intra-molecular cyclization leading to formation of a cyclic urea, carbamate or thiocarbamate.
Inventors:
Jenkins, Thomas E.
Kolesnikov, Alexandre
Kolesnikov, Alexandre
Application Number:
JP2009512310A
Publication Date:
December 18, 2013
Filing Date:
May 24, 2007
Export Citation:
Assignee:
Pharmacophore, Incorporated
International Classes:
C07D489/02; A61K31/485; A61P25/04; A61P43/00; C07D489/08
Domestic Patent References:
| JP2005524648A | ||||
| JP2006515622A | ||||
| JP2004523480A | ||||
| JP2002540073A |
Foreign References:
| WO2005032474A1 |
Attorney, Agent or Firm:
Hidesaku Yamamoto
Takaaki Yasumura
Natsuki Morishita
Takaaki Yasumura
Natsuki Morishita