Title:
クレアチンプロドラッグ、その組成物、及びその使用方法
Document Type and Number:
Japanese Patent JP7037597
Kind Code:
B2
Abstract:
The invention describes membrane permeable creatine prodrugs, pharmaceutical compositions comprising membrane permeable creatine prodrugs, and methods of treating diseases such as ischemia, heart failure, neurodegenerative disorders and genetic disorders affecting the creatine kinase system comprising administering creatine prodrugs or pharmaceutical compositions thereof. The invention also describes treating a genetic disease affecting the creatine kinase system, such as, for example, a creatine transporter disorder or a creatine synthesis disorder comprising administering creatine prodrugs or pharmaceutical compositions thereof.
Inventors:
Bull Baker William F.
Application Number:
JP2020072408A
Publication Date:
March 16, 2022
Filing Date:
April 14, 2020
Export Citation:
Assignee:
FARMINGTON PHARMA DEVELOPMENT
International Classes:
C07D271/06; A61K31/4245; A61K31/5395; A61P9/00; A61P9/10; A61P21/00; A61P25/00; A61P25/18; C07D273/04; C07D413/12
Foreign References:
| WO2014018570A1 | ||||
| WO2014019855A1 | ||||
| WO2014097335A1 | ||||
| WO2008101310A1 | ||||
| WO2007146086A1 | ||||
| WO2005108370A1 |
Attorney, Agent or Firm:
Hiroki Masaki
Seiji Ozawa
Yusaku Tokai
Horiuchi Makoto
Masako Yamauchi
Shuichi Sonomoto
Akihiro Yamamura
Hiroyuki Tomita
Seiji Ozawa
Yusaku Tokai
Horiuchi Makoto
Masako Yamauchi
Shuichi Sonomoto
Akihiro Yamamura
Hiroyuki Tomita