Title:
ペプチド系抗腫瘍薬の創製
Document Type and Number:
Japanese Patent JP7201181
Kind Code:
B2
Abstract:
An object of the present invention is to provide an echinomycin derivative that has anti-cancer activity equal to or greater than that of echinomycin, and a production method therefor based on a chemical procedure. Provided are an echinomycin derivative represented by formula (I), and a production method therefor based on a chemical procedure.
Inventors:
Satoshi Ichikawa
Keita Kojima
Mikihiro Fujitani
Hiroaki Konishi
Keita Kojima
Mikihiro Fujitani
Hiroaki Konishi
Application Number:
JP2019569581A
Publication Date:
January 10, 2023
Filing Date:
January 31, 2019
Export Citation:
Assignee:
National University Corporation Hokkaido University
National University Corporation Asahikawa Medical University
National University Corporation Asahikawa Medical University
International Classes:
C07K11/02; A61K38/12; A61K38/15; A61P35/00
Foreign References:
| US20090053769 |
Other References:
KIM Yun Bong, et al.,Synthesis and biological activity of new quinoxaline antibiotics of echinomycin analogues,Bioorganic & Medicinal Chemistry Letters,2004年,Vol.14,p.541-544,Figure 1, Scheme 1,2
HATTORI Kozo, et al.,Solution-Phase Synthesis and Biological Evaluation of Triostin A and its Analogues,Organic & Biomolecular Chemistry,2016年,Vol.14, No.6,p.2090-2111,Scheme 1,2
HATTORI Kozo, et al.,Solution-Phase Synthesis and Biological Evaluation of Triostin A and its Analogues,Organic & Biomolecular Chemistry,2016年,Vol.14, No.6,p.2090-2111,Scheme 1,2
Attorney, Agent or Firm:
Seiji Ohno
Yuko Matsutoya
Shinsuke Umeda
Yu Morita
Chisuke Konno
Nobuto Oki
Yuko Matsutoya
Shinsuke Umeda
Yu Morita
Chisuke Konno
Nobuto Oki