Title:
CRYSTAL OF AZABICYCLO RING COMPOUND
Document Type and Number:
Japanese Patent JP2023070165
Kind Code:
A
Abstract:
To provide a compound having KDM5 inhibitory activity and a suitable form thereof for pharmaceutical ingredients.SOLUTION: A compound disclosed herein has strong KDM5 inhibitory activity as well as excellent metabolic stability and also can exist in the brain at high concentrations, so that it is suitable as an agent for preventing and/or treating KDM5-associated diseases, particularly, diseases such as cancer, Huntington's disease, Alzheimer's disease. The compound is also suitable as a pharmaceutical ingredient.SELECTED DRAWING: None
Inventors:
KAKUUCHI AKITO
HIRAMATSU ATSUSHI
HIRAMATSU ATSUSHI
Application Number:
JP2022177002A
Publication Date:
May 18, 2023
Filing Date:
November 04, 2022
Export Citation:
Assignee:
ONO PHARMACEUTICAL CO
International Classes:
C07D413/14; A61K31/422; A61P1/16; A61P3/10; A61P9/00; A61P9/10; A61P17/06; A61P25/00; A61P25/14; A61P25/16; A61P25/18; A61P25/22; A61P25/24; A61P25/28; A61P29/00; A61P31/12; A61P35/00; A61P37/02; A61P37/08
Attorney, Agent or Firm:
Atsushi Aoki
Shinji Mihashi
Youichi Watanabe
Masaru Nakajima
Tatsunori Ikeda
Shinji Mihashi
Youichi Watanabe
Masaru Nakajima
Tatsunori Ikeda
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