Title:
NEMOのCC2-LZドメインの結晶構造
Document Type and Number:
Japanese Patent JP5529759
Kind Code:
B2
Abstract:
The invention relates to a crystal of the CC2-LZ domain of the NEMO protein, in which the three-dimensional structure has been determined by X-ray diffraction at a resolution of about 3.25 A. The invention also relates to methods for the crystallization of the CC2-LZ domain. The CC2-LZ crystals and the information derived from the crystalline structures thereof are used for identifying and designing compounds interacting with CC2-LZ.
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Inventors:
Ag, Fabrice
Charavari, Jeanne
Duqueroy, Stefan
Fontan, Elizabeth
Grubisha, Olivera
Kaminska, Monica Dorota
Michelle Vero
Cordia, Florence
Charavari, Jeanne
Duqueroy, Stefan
Fontan, Elizabeth
Grubisha, Olivera
Kaminska, Monica Dorota
Michelle Vero
Cordia, Florence
Application Number:
JP2010545522A
Publication Date:
June 25, 2014
Filing Date:
February 05, 2009
Export Citation:
Assignee:
Réra Bora Toir Servier
International Classes:
C07K14/47; G01N23/20; G16B15/30; C12N15/09
Domestic Patent References:
| JP2004533597A |
Other References:
Protein Sci.,2007 Sep,16(9),p.2013-22
Attorney, Agent or Firm:
Hajime Tsukuni
Yasuo Yanagibashi
Satoko Ito
Keiko Ozawa
Yasuhiro Oguni
Yoko Tanaka
Yoshinori Ikukawa
Akio Shibata
Suzuki Otoya
Yasuo Yanagibashi
Satoko Ito
Keiko Ozawa
Yasuhiro Oguni
Yoko Tanaka
Yoshinori Ikukawa
Akio Shibata
Suzuki Otoya