Title:
結晶形態のメロペネム中間体
Document Type and Number:
Japanese Patent JP2008501657
Kind Code:
A
Abstract:
The present invention relates to the compound (4R,5S,6S)-(p-nitrobenzyl) 3-[[(3S,5S)-1(-p-nitrobenzyloxycarbonyl)-5-(dimethylaminocarbonyl)-3-pyrrolidinyl]thio]-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylate in crystalline form, as well as a process for the production of this crystalline compound in alkyl alkanoates, and its usage in a process for producing meropenem.
Inventors:
Nadenitz, Peter
Storm me
Kreminger, Peter
Storm me
Kreminger, Peter
Application Number:
JP2007513849A
Publication Date:
January 24, 2008
Filing Date:
June 01, 2005
Export Citation:
Assignee:
SANDOZ AKTIENGESELLSCHAFT
International Classes:
C07D477/00; C07D477/20; C07D487/04
Domestic Patent References:
| JPS6479180A | 1989-03-24 | |||
| JPS6434986A | 1989-02-06 | |||
| JPH06340667A | 1994-12-13 | |||
| JPH06321947A | 1994-11-22 | |||
| JPH06316559A | 1994-11-15 | |||
| JPS60233076A | 1985-11-19 | |||
| JPS62103084A | 1987-05-13 | |||
| JPS60104088A | 1985-06-08 | |||
| JPS6479181A | 1989-03-24 |
Attorney, Agent or Firm:
Yoshio Kawaguchi
Makoto Ono
Chihiro Watanabe
Kenkyo Kanayama
Katsuma Osaki
Mitsuaki Tsubokura
Makoto Ono
Chihiro Watanabe
Kenkyo Kanayama
Katsuma Osaki
Mitsuaki Tsubokura