Title:
５－メチル－（６Ｓ）－テトラヒドロ葉酸及びＬ－バリンエチルエステルの結晶性塩
Document Type and Number:
Japanese Patent JP7422124
Kind Code:
B2
Abstract:
The present invention refers to a crystalline salt comprising 5-methyl-(6S)-tetrahydrofolic acid and L-valine ethyl ester wherein the molar ratio of 5-methyl-(6S)-tetrahydrofolic acid and L-valine ethyl ester is from 1:0.3 to 1:3.0 (in mol/mol) and/or hydrates and/or solvates thereof as well as to a process of obtaining the same.
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Inventors:
Moser, Rudolph
grain, viola
Beni Stamm, Ruth
Blatter, Fritz
Sieragiewicz, Martin
grain, viola
Beni Stamm, Ruth
Blatter, Fritz
Sieragiewicz, Martin
Application Number:
JP2021500142A
Publication Date:
January 25, 2024
Filing Date:
July 02, 2019
Export Citation:
Assignee:
Merck Patent Gesellschaft mit beschraenkter Haftung
International Classes:
C07D475/04; A61K31/519; A61P7/00; A61P7/06; A61P9/00; A61P19/10; A61P25/00; A61P25/24; A61P25/28; C07C227/42; C07C229/08
Domestic Patent References:
| JP2000327680A | ||||
| JP2015506941A |
Foreign References:
| US20160207925 |
Attorney, Agent or Firm:
Akio Miyazaki
Masaaki Ogata
Masaaki Ogata