Title:
５－メチル－（６Ｓ）－テトラヒドロ葉酸の結晶性ナトリウム塩
Document Type and Number:
Japanese Patent JP7296885
Kind Code:
B2
Abstract:
The present invention is directed to a crystalline sodium salt of 5-methyl-(6S)-tetrahydrofolic acid wherein the molar ratio of 5-methyl-(6S)-tetrahydrofolic acid to sodium is from 1:1.51 to 1:2.5 and/or hydrates and/or solvates thereof, as well as, a process of obtaining the same.
Inventors:
Moser, Rudolph
grain, viola
Blatter, Fritz
Sieragiewicz, Martin
Beni Stamm, Ruth
Rüttimann, Marx
grain, viola
Blatter, Fritz
Sieragiewicz, Martin
Beni Stamm, Ruth
Rüttimann, Marx
Application Number:
JP2019553844A
Publication Date:
June 23, 2023
Filing Date:
March 28, 2018
Export Citation:
Assignee:
Merck Patent Gesellschaft mit beschraenkter Haftung
International Classes:
C07D475/04; A23L33/10; A61K9/02; A61K9/08; A61K9/10; A61K9/14; A61K9/16; A61K9/19; A61K9/20; A61K9/28; A61K9/48; A61K31/519; A61P3/00; A61P3/02; A61P5/50; A61P7/06; A61P9/00; A61P19/10; A61P25/00; A61P25/24; A61P25/28
Domestic Patent References:
| JP11116482A | ||||
| JP2000327680A | ||||
| JP2015506941A |
Foreign References:
| US5124452 | ||||
| WO2013025203A1 | ||||
| WO2015193778A1 |
Other References:
平山令明,有機化合物結晶作製ハンドブック,2008年,p.17-23,37-40,45-51,57-65
川口洋子ら,医薬品と結晶多形,生活工学研究,2002年,Vol.4, No.2,p.310-317
川口洋子ら,医薬品と結晶多形,生活工学研究,2002年,Vol.4, No.2,p.310-317
Attorney, Agent or Firm:
Akio Miyazaki
Masaaki Ogata
Masaaki Ogata