Title:
テトラヒドロイソキノリンの塩の結晶、当該結晶を含んだ医薬組成物及び当該結晶の製造方法
Document Type and Number:
Japanese Patent JP6823714
Kind Code:
B2
Abstract:
The present invention discloses a salt derivative of 1-(3-methanesulfonamidobenzyl)-6-methoxy-7-benzyloxy-1,2,3,4-tetrahydroisoquinoline shown in formula I. The salt derivative has a solubility in water of not less than 3.0 nmol/mL or 1.8 mg/mL:The salt derivative has a solubility in water of not less than 3.0 nmol/mL or 1.8 mg/mL
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Inventors:
Jie, Mayhua
Zan, pretend
C, Taiji
Zon, The Alien
Zan, pretend
C, Taiji
Zon, The Alien
Application Number:
JP2019512752A
Publication Date:
February 03, 2021
Filing Date:
August 30, 2017
Export Citation:
Assignee:
China State Institute of Pharmaceutical Industry
Shanghai Institute of Pharmaceutical Industry
Shanghai Institute of Pharmaceutical Industry
International Classes:
C07D217/18; A61K31/472; A61P9/06
Foreign References:
| CN104693115A | ||||
| CN1566098A | ||||
| CN101619038A |
Other References:
C.G.WERMUTH編,「最新 創薬化学 下巻」,株式会社 テクノミック,1999年,pp.347-365
PHARM TECH JAPAN,2002年,Vol.18, No.10,pp.1629-1644
PHARM TECH JAPAN,2002年,Vol.18, No.10,pp.1629-1644
Attorney, Agent or Firm:
Isono International Patent and Trademark Office