Title:
シアノ置換ジヒドロピリミジン化合物および疾患を治療するためのそれらの使用
Document Type and Number:
Japanese Patent JP2004529139
Kind Code:
A
Abstract:
The present invention provides compounds of formula I and pharmaceutically acceptable salts thereof. The formula I compounds induce mitotic arrest thereby making them useful as anti-cancer agents. The formula I compounds are also useful for the treatment of other diseases which can be treated by inducing mitotic arrest.
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Inventors:
Louis Jay Lombard
Lawrence I Wu
Lawrence I Wu
Application Number:
JP2002577796A
Publication Date:
September 24, 2004
Filing Date:
March 26, 2002
Export Citation:
Assignee:
BRISTOL-MYERS SQUIBB COMPANY
International Classes:
A61K31/505; A61K31/506; A61K31/513; A61K45/00; A61P1/04; A61P1/16; A61P9/00; A61P9/06; A61P9/10; A61P9/14; A61P13/12; A61P17/06; A61P19/00; A61P19/02; A61P21/00; A61P21/04; A61P25/14; A61P25/16; A61P25/28; A61P27/16; A61P29/00; A61P35/00; A61P35/02; A61P37/06; C07D211/90; C07D239/22; C07D401/04; C07D401/10; C07D403/10; C07D403/12; C07D405/04; C07D239/42; C07D409/04; C07D409/06; C07D409/10; C07D409/12; C07D413/04; C07D413/10; C07D417/04; (IPC1-7): C07D239/22; A61K31/505; A61K31/513; A61K45/00; A61P1/04; A61P1/16; A61P9/00; A61P9/06; A61P9/10; A61P13/12; A61P17/06; A61P19/00; A61P19/02; A61P21/00; A61P21/04; A61P25/14; A61P25/16; A61P25/28; A61P27/16; A61P29/00; A61P35/00; A61P35/02; A61P37/06; C07D401/10; C07D403/10; C07D405/04; C07D409/04; C07D409/10; C07D409/12; C07D413/04; C07D417/04
Attorney, Agent or Firm:
Kyousei Tamura
Toshio Ueda
Nagatoshi Shinagawa
Toshio Ueda
Nagatoshi Shinagawa