CYCLIC AMINE, METHOD OF PRODUCING THE SAME AND USE THEREOF

Title:

CYCLIC AMINE, METHOD OF PRODUCING THE SAME AND USE THEREOF

Document Type and Number:

Japanese Patent JP3814136

Kind Code:

B2

Abstract:

PROBLEM TO BE SOLVED: To provide a compound that shows excellent CCR5 antagonistic action and is useful as a prophylactic and therapeutic agent for the HIV infection to human peripheral blood mononuclear cells, particularly for AID.
SOLUTION: This invention is the compound represented by formula 1 or salts thereof. As a compound of this invention, are cited N-(3- chlorophenyl)-1-(methyl-sulfonyl)-N-{3-[4-({4-[(methylsulfonyl)amino]phenyl}- sulfonyl)-1-piperidinyl]propyl)-4-piperidinecarbo-xamide, N-(3,4- dichlorophenyl)-1-(methylsulfonyl)-N-{3-[4-({4-[(methylsulfonyl)amino]phenyl) sulfonyl)-1-piperidinyl]propyl)-4-piperidinecarboxamide.

Inventors:

Shinichi Imamura
Shohei Hashiguchi
Taeko Hattori
Nishimura Nori
Naoyuki Kanzaki
Masanori Baba
Yoshihiro Sugihara

Application Number:

JP2000302841A

Publication Date:

August 23, 2006

Filing Date:

September 29, 2000

Export Citation:

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Assignee:

Takeda GmbH

International Classes:

C07D211/62; A61K31/427; C07D211/66; A61K31/4355; A61K31/437; A61K31/4427; A61K31/443; A61K31/4433; A61K31/445; A61K31/454; A61K31/4545; A61K31/4709; A61K31/472; A61K31/4725; A61K31/496; A61K31/497; A61K31/498; A61K31/5025; A61K31/506; A61K31/513; A61K31/5377; A61K31/5513; A61K31/7072; A61K31/708; A61K45/00; A61P31/18; A61P43/00; C07D211/58; C07D211/70; C07D211/74; C07D211/96; C07D401/12; C07D401/14; C07D405/12; C07D405/14; C07D409/14; C07D413/12; C07D413/14; C07D417/04; C07D417/14; C07D471/04; C07D471/14; C07D471/16; C07D487/04; C07D487/14; A61K; A61P; C07D; (IPC1-7): C07D211/62; A61K31/427; A61K31/437; A61K31/4545; A61K31/472; A61K31/4725; A61K31/496; A61K31/498; A61K31/5025; A61K31/506; A61K31/513; A61K31/5377; A61K31/5513; A61K31/7072; A61K31/708; A61K45/00; A61P31/18; A61P43/00; C07D211/58; C07D211/96; C07D401/12; C07D401/14; C07D405/12; C07D409/14; C07D413/12; C07D413/14; C07D417/14; C07D471/04; C07D471/16; C07D487/04

Domestic Patent References:

JP52062279A
JP62089679A

Foreign References:

WO2000066551A1
WO1999004794A1
WO1999017773A1
WO1994022861A1

Attorney, Agent or Firm:

Takashima Ichi
Shuichi Takahashi
Tsutomu Uchiyama

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