Title:
環状アミノ酸誘導体
Document Type and Number:
Japanese Patent JP2004523466
Kind Code:
A
Abstract:
Novel compounds of the formula I in which R1, R2, R2', R2'', R3, R4, R5, R5', R5'', R5''', R5'''', X, Y, U, V and W are as defined in Patent claim 1, are inhibitors of coagulation factors Xa and VIIa and can be employed fr the treatment of thromboses, myocardilal infarction, arteriosclerosis, inflammation, apoplexia, angina pectoris, restenosis after angioplasty, claudicatio intermittens, tumours, tumour diseases and/or tumour metastases.
Inventors:
Uraszik, Horst
Dolsh, Dieter
Medellsky, Werner
Tsar Krachidis, Christos
Burns, christopher
Glitz, johannes
Dolsh, Dieter
Medellsky, Werner
Tsar Krachidis, Christos
Burns, christopher
Glitz, johannes
Application Number:
JP2002512172A
Publication Date:
August 05, 2004
Filing Date:
July 03, 2001
Export Citation:
Assignee:
Merck Patent Gesellschaft mit beschraenkter Haftung
International Classes:
A61K31/397; A61K31/402; A61K31/4166; A61K31/421; A61K31/426; A61K31/4439; A61K31/451; A61K31/495; A61K45/00; A61P7/02; A61P7/04; A61P9/00; A61P9/10; A61P25/00; A61P29/00; A61P35/00; A61P43/00; C07D205/04; C07D207/16; C07D207/28; C07D211/34; C07D211/60; C07D233/34; C07D233/36; C07D263/06; C07D263/24; C07D277/06; C07D401/04; C07D413/12; C07D295/20; (IPC1-7): C07D205/04; A61K31/397; A61K31/402; A61K31/4166; A61K31/421; A61K31/426; A61K31/4439; A61K31/451; A61K31/495; A61K45/00; A61P7/02; A61P7/04; A61P9/00; A61P9/10; A61P25/00; A61P29/00; A61P35/00; A61P43/00; C07D207/16; C07D207/28; C07D211/60; C07D233/34; C07D233/36; C07D263/06; C07D263/24; C07D277/06; C07D295/20; C07D401/04; C07D413/12
Attorney, Agent or Firm:
Kiyoji Kuzuwa